Medications

Dexamethasone underused for adults hospitalized with COVID-19

(HealthDay)—For adults hospitalized with COVID-19, dexamethasone and remdesivir use increased over time, although dexamethasone is still somewhat underused, according to a study published online Aug. 17 in the Annals of ...

page 1 from 10

Hydroxychloroquine

Hydroxychloroquine is an antimalarial drug, sold under the trade names Plaquenil,Axemal(In India), Dolquine, and Quensyl, also used to reduce inflammation in the treatment of rheumatoid arthritis (see disease-modifying antirheumatic drugs) and lupus. Hydroxychloroquine differs from chloroquine by the presence of a hydroxyl group at the end of the side chain: The N-ethyl substituent is beta-hydroxylated. It is available for oral administration as hydroxychloroquine sulfate (plaquenil) of which 200 mg contains 155 mg base in chiral form. Hydroxychloroquine has similar pharmacokinetics to chloroquine, with quick gastrointestinal absorption and is eliminated by the kidney. Cytochrome P450 enzymes (CYP 2D6, 2C8, 3A4 and 3A5) N-desethylated Hydroxychloroquine to Ndesethylhydroxychloroquine. ,

This text uses material from Wikipedia, licensed under CC BY-SA