Medications

Drug interaction causes hypotension

The commonly used muscle relaxant tizanidine can lower blood pressure. Tizanidine is metabolized by the enzyme CYP1A2, and concurrent use of tizanidine and a CYP1A2 inhibitor, such as ciprofloxacin, greatly increases tizanidine ...

Surgery

Algorithm predicts dangerous low blood pressure during surgery

Scientists have developed an algorithm that predicts potentially dangerous low blood pressure, or hypotension, that can occur during surgery. The algorithm identifies hypotension 15 minutes before it occurs in 84 percent ...

Other

A better way of estimating blood loss

Research suggests that there may be a better way of measuring blood loss due to trauma than the current method, finds an article in BioMed Central's open access journal Critical Care. The study shows that base deficit (BD) ...

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