Cancer

Study finds way to potentially improve immunotherapy for cancer

A new study has identified a drug that potentially could make a common type of immunotherapy for cancer even more effective. The study in laboratory mice found that the drug dasatinib, which is FDA-approved to treat certain ...

Neuroscience

Scientists create new map of brain's immune system

A team of researchers under the direction of the Medical Center—University of Freiburg has created an entirely new map of the brain's own immune system in humans and mice. The scientists demonstrated for the first time ...

Immunology

How the 'Iron Man' of immune cells helps T cells fight infection

The immune system's killer T cells are crucial in fighting viral infections. A fraction of them, called 'memory cells', live on once infection is controlled in order to fight re-infection by the same virus. They are of great ...

Diseases, Conditions, Syndromes

'Killer' cells raise hope of universal flu vaccine

Scientists said Monday they had discovered immune cells that can fight all known flu viruses in what was hailed as an "extraordinary breakthrough" that could lead to a universal, one-shot vaccine against the killer disease.

Medical research

CRISPR gene editing makes stem cells 'invisible' to immune system

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory ...

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White blood cell

White blood cells (WBCs), or leukocytes (also spelled "leucocytes"), are cells of the immune system defending the body against both infectious disease and foreign materials. Five different and diverse types of leukocytes exist, but they are all produced and derived from a multipotent cell in the bone marrow known as a hematopoietic stem cell. Leukocytes are found throughout the body, including the blood and lymphatic system.

The number of leukocytes in the blood is often an indicator of disease. There are normally between 4×109 and 1.1×1010 white blood cells in a litre of blood, making up approximately 1% of blood in a healthy adult. An increase in the number of leukocytes over the upper limits is called leukocytosis, and in leukopenia, this number is much lower than the lower limit. The physical properties of leukocytes, such as volume, conductivity, and granularity, may change due to activation, the presence of immature cells, or the presence of malignant leukocytes in leukemia.

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