A group of Massachusetts General Hospital (MGH) investigators is proposing that targeting immune checkpoints—molecules that regulate the activity of the immune system—in immune cells called microglia could reduce the ...
Oct 17, 2018
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Scientists from the German Cancer Research Center (DKFZ) identify a new and surprising function of a membrane protein on the surface of cancer cells: It supports and stabilizes an important "co-stimulatory" factor that enhances ...
Sep 13, 2023
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A team of researchers affiliated with Johns Hopkins University and Memorial Sloan Kettering Cancer Center has found some of the reasons for different responses to anti-PD-1 checkpoint blockade immunotherapy in cancer patients. ...
You awake in the middle of the night from a nightmare.
Feb 10, 2020
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An international team involving Vanderbilt researchers has discovered that a new "checkpoint" protein on immune system cells is active in tumors, and that blocking it—in combination with other treatments—is a successful ...
Feb 22, 2019
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Immunotherapy is a way of treating cancer by reprogramming the patient's immune system to attack their tumor. This cutting-edge approach has significantly impacted the treatment of cancer patients, and already boasts cases ...
Jan 10, 2023
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Many patients with cancer receive immune checkpoint inhibitors that strengthen their immune response against tumor cells. While the medications can be life-saving, they can also cause potentially life-threatening side effects ...
Apr 12, 2021
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Many people don't realize that the trillions of bacteria, viruses, and fungi residing within the gastrointestinal tract—collectively called the gut microbiome—are connected to overall health, and specifically to cancer.
Jun 24, 2021
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Cancer immunotherapy—empowering a patient's own immune system to clear away tumors on its own—holds great promise for some patients. But for other patients, immunotherapy just doesn't work.
Aug 17, 2020
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Immunotherapy is showing great promise for treating cancer. But so far, this approach has been effective in only about 20% of all cancers. To advance those results, researchers are looking for new ways to mobilize the immune ...
Feb 21, 2020
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