Oncology & Cancer

Review explores therapeutic targets in tumor microenvironment

The tumor microenvironment (TME) is the ecosystem surrounding a tumor, which usually consists of non-tumoral cells and molecules they produce and release. The interplay between tumor cells and the TME significantly impacts ...

Diseases, Conditions, Syndromes

Advancing diagnostics for lupus nephritis

The nature of a typical clinical test for lupus nephritis (LN), an inflammation of the kidneys and a leading cause of mortality in lupus patients, is fraught with difficulty. The invasive renal biopsy can be painful and may ...

Immunology

How dendritic cells activate the immune system

The specific or acquired immune system of vertebrates is a powerful weapon against pathogens and pathologically altered body cells. Here, T cells play a special role. After activation, they can systematically kill off target ...

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