Diseases, Conditions, Syndromes

Researchers discover pathways to severe COVID-19 in children

Researchers have discovered the blood clotting and immune protein pathways that are activated in severe cases of COVID-19 in children, paving the way for earlier diagnosis and more targeted treatments.

Neuroscience

Findings open way for personalized multiple sclerosis treatment

Currently available therapies to treat multiple sclerosis (MS) lack precision and can lead to serious side effects. Researchers at Karolinska Institutet in Sweden have now developed a method for identifying the immune cells ...

Immunology

How one inflammatory disorder exacerbates another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, ...

Genetics

Scientists find a genetic cause of lupus

An international team of researchers has identified DNA mutations in a gene that senses viral RNA, as a cause of the autoimmune disease lupus, with the finding paving the way for the development of new treatments.

Medications

Promising biologic drug for treating chronic lung disease

NUS scientists have discovered a novel property of a protein found in human lungs that could lead to the development of biologic drugs to treat chronic obstructive pulmonary disease (COPD), a debilitating, progressive lung ...

Diseases, Conditions, Syndromes

A new understanding of how the immune system deals with malaria

By analyzing samples from patients who have been treated for malaria in Sweden, researchers at Karolinska Institutet can now describe how the immune system acts to protect the body after a malaria infection. The results, ...

Alzheimer's disease & dementia

Key signaling pathway in immune cells could be new Alzheimer's target

Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other neurodegenerative diseases, suggests a study by Weill ...

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