Mice reach the twilight of their lives at around age two, the rough equivalent of 80 in human years. And when researchers introduce specific mutations into mice and then age them up, the mice can grow forgetful and irritable—eventually ...
Jan 10, 2024
0
16
Researchers at Weill Cornell Medicine have cataloged the cellular response to stroke in a preclinical model, identifying the immune cells involved and the roles they may play in the days and weeks following a stroke.
Jan 10, 2024
0
23
In order for immune cells to do their job, they need to know against whom they should direct their attack. Research teams at the University of Würzburg have identified new details in this process.
Dec 8, 2023
0
52
A new paper in Science Advances details how scientists have succeeded in mapping a central part of the immune system—the HLA class II molecules—while accurately predicting how they display fragments of pathogens on the ...
Nov 27, 2023
0
25
Researchers at Weill Cornell Medicine have demonstrated how amyloid beta, a peptide associated with Alzheimer's disease, can interact with a protein receptor on immune cells in the brain. This triggers a reaction that damages ...
Nov 8, 2023
0
44
Clostridioides difficile (C. diff) intestinal infections can cause severe, debilitating diarrhea in patients who are hospitalized or on immunosuppressive therapies. The infections can be very hard to eradicate, roaring back ...
Oct 26, 2023
0
21
If you're one of the nearly 25 percent of people with the gene variant known as APOE4, you have a higher-than-average chance of developing Alzheimer's disease. But while scientists have long known that APOE4 leads to changes ...
Oct 20, 2023
0
57
Researchers at Harvard Medical School have discovered that a molecule made by Streptococcus pyogenes—the bacterium that causes strep throat and other infections—could help explain several long-standing medical mysteries, ...
Oct 6, 2023
0
92
Cancer immunotherapy drugs called PD-1 inhibitors are widely used to stimulate the immune system to fight cancer, but many patients either don't respond or develop resistance to them. A new small-molecule drug candidate being ...
Oct 4, 2023
0
31
An international team of scientists has developed a method for simultaneously detecting thousands of lipid molecules that are displayed to T cells in the human immune system.
Sep 18, 2023
0
34
