Oncology & Cancer

Scientists discover new immunosuppressive mechanism in brain cancer

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma—a serious and often fatal brain cancer—suppresses the immune system so that the tumor can grow ...

HIV & AIDS

Study reveals how a Rab protein controls HIV-1 replication

HIV-1 replication requires the coordinated movement of the virus's components toward the plasma membrane of an immune cell, where the virions are assembled and ultimately released. A study in The Journal of Cell Biology reveals ...

Oncology & Cancer

Putting the STING into cancer immunotherapy

Immune checkpoint blockade therapies have been revolutionary in the treatment of some cancer types, emerging as one of the most promising treatments for diseases such as melanoma, colon cancer and non-small cell lung cancer.

Medical research

Whole-parasite malaria vaccine shows promise in clinical trial

For the first time, a malaria vaccine that uses the entire malaria parasite has proven safe and shown promise to produce a strong immune response in a clinical trial, according to a new study co-authored by researchers at ...

Oncology & Cancer

New rules for anticancer vaccines

Scientists have found a way to find the proverbial needle in the cancer antigen haystack, according to a report published in The Journal of Experimental Medicine.

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