Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T-cell therapy for treatment of solid tumors. The results were published today in ...
Jun 22, 2022
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Androgen receptor (AR) signaling affects response to BRAF/MEK inhibitor therapy in both males and females with melanoma, researchers from The University of Texas MD Anderson Cancer Center showed in a study published today ...
Jun 15, 2022
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Before a patient can undergo T cell therapy designed to target cancerous tumors, the patient's entire immune system must be destroyed with chemotherapy or radiation. The toxic side effects are well known, including nausea, ...
Jun 8, 2022
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Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind of lengthy battle, they can become exhausted, or unable to function properly. One immunotherapy that revitalizes ...
Apr 18, 2022
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Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer. Compared to traditional drugs, engineered immune cells are more precise and sophisticated in their ability ...
Apr 15, 2022
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Scientists at St. Jude Children's Research Hospital have evaluated how vaccination against, and infection with, SARS-CoV-2 affects the immune system. The results confirm that immunity by infection is not better than vaccination ...
Apr 5, 2022
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Indiana University School of Medicine researchers have found that niacin limits Alzheimer's disease progression when used in models in the lab, a discovery that could potentially pave the way toward therapeutic approaches ...
Mar 23, 2022
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The first FDA-approved gene therapies are living drugs: immune cells taken from cancer patients engineered to target tumor cells. However, for many patients, these advanced therapies do not result in a long-lasting remission. ...
Mar 16, 2022
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Investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have discovered how a drug for multiple sclerosis interacts with its targets, a finding that may pave the way for better treatments.
Mar 4, 2022
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Chronic inflammatory bowel disease (IBD) is becoming increasingly widespread. Until now, however, the underlying causes of the inflammation responses were unclear. Scientists at the Technical University of Munich (TUM) have ...
Feb 2, 2022
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