Oncology & Cancer

Researchers convert pro-tumor macrophages into cancer killers

Epithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer therapies and to become highly metastatic. In a paper published in Cancer Research, University ...

Immunology

It's Fab! A hidden touch of antibody

In our immune system, antibodies recognize viruses, bacteria and even cancer cells through their Fab arms, initiating recruitment of leucocytes for the destruction of these invaders. The recruitment is mediated by receptors ...

Oncology & Cancer

New immune system understanding may help doctors target cancer

Your immune system's natural killer cells recognize and attack two major kinds of danger—cells infected by viruses and cells affected by cancer. When natural killer (NK) cells see a cancer cell, they kill it (naturally...). ...

Oncology & Cancer

New lipid signaling target may improve T cell immunotherapy

The immune system surveils our body looking for things that don't belong, often bacteria and viruses. While cancer cells are abnormal cells that undergo unregulated cell growth, they are good at evading detection by the immune ...

Medical research

New clues on stem cell transplant rejection revealed in study

In 2006, scientists discovered a way to "reprogram" mature cells—adult skin cells, for example—into stem cells that could, in principle, give rise to any tissue or organ in the body. Many assumed it was only a matter ...

Medical research

Researchers describe building blocks of HIV's protective shell

The genome of the HIV-1 virus is protected by a conical-shaped protein shell called a capsid, which performs many functions crucial to viral infection—shielding the virus from the immune system, attaching to cell's transport ...

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