Researchers at Mayo Clinic's Center for Individualized Medicine have devised an immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively ...
Apr 13, 2022
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Acute lymphoblastic leukemia (ALL) cells from patients whose cancers did not respond to CD19-targeted CAR T therapy had gene regulation signatures that could potentially facilitate treatment resistance, according to results ...
Apr 12, 2022
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Cardamonin—a natural compound found in the spice cardamom and other plants—could have therapeutic potential for triple-negative breast cancer, according to a new study using human cancer cells. The findings also show ...
Apr 3, 2022
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A new study from researchers at the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital and Houston Methodist Hospital shows that cancer patients who receive treatment with genetically ...
Mar 30, 2022
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A new approach from Penn Medicine researchers could cut the time it takes to alter patients' immune cells for infusion back into the body to find and attack cancer. The cell manufacturing process for this type of immunotherapy ...
Mar 29, 2022
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An experimental cream-based gene therapy may soon become the first U.S. government-approved means for treating a rare and devastating skin disease that produces "butterfly children."
Mar 29, 2022
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Antiretroviral therapy (ART) is highly effective at controlling HIV infections, but the virus never completely goes away. Instead, it hides in roughly one in every 1 million immune cells.
Mar 23, 2022
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Meningiomas, tumors of the membranes (meninges) surrounding the brain and spinal cord, are the most common tumors of the central nervous system. Although most meningiomas are low grade and cause few or no symptoms, a subset, ...
Mar 23, 2022
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The first FDA-approved gene therapies are living drugs: immune cells taken from cancer patients engineered to target tumor cells. However, for many patients, these advanced therapies do not result in a long-lasting remission. ...
Mar 16, 2022
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A collaborative study led by the Monash Biomedicine Discovery Institute (BDI) has discovered a new immune checkpoint that may be exploited for cancer therapy.
Mar 8, 2022
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