Immune activation in a pregnant woman can have negative effects on the development of fetal brain microglia—or macrophage immune cells in the brain—and even lead to neurodevelopmental disorders in newborns.
Jun 10, 2024
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Checkpoint immunotherapy utilizing PD-1 blockade has become the standard of care for metastatic melanoma. While this treatment is effective in 40% of patients, the other 60% develop resistance, leading to tumor regrowth. ...
Jun 10, 2024
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When scientists transplanted the gut microbes of aged mice into young "germ-free" mice—raised to have no gut microbes of their own—the recipient mice experienced an increase in inflammation that parallels inflammatory ...
Jun 10, 2024
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Why does hepatitis E become chronic in some patients, and why do medications not work? To find out, an international research team led by scientists from Bochum observed a patient with chronic hepatitis E infection over a ...
Jun 10, 2024
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Do you want the bad news, good news or better news? The bad news is that cancer continues to be the second leading cause of death in the United States, trailing heart disease. The good news is that overall cancer mortality ...
Jun 7, 2024
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Cytotoxic T cells are an important component of the immune system. Once activated, they differentiate into either short-lived effector cells or long-lived memory cells. Studies by researchers at ETH Zurich have found that ...
Jun 6, 2024
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In an advance that could transform bladder cancer treatment, a novel combination of cretostimogene grenadenorepvec and pembrolizumab has shown remarkable efficacy in patients with Bacillus Calmette-Guérin (BCG)-unresponsive ...
Jun 6, 2024
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Johns Hopkins Medicine scientists say they have developed an artificial lymph node with the potential to treat cancer, according to a new study in mice and human cells. The newly developed lymph node—a sac filled with immune ...
Jun 6, 2024
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A team of medical researchers at Huazhong University of Science and Technology, in China, working with a colleague from Nanyang Technological University, in Singapore, has developed a noninvasive way to monitor biomarkers ...
In a major advance for the treatment of the deadly brain cancer glioblastoma, Northwestern Medicine scientists have used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy ...
Jun 6, 2024
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