Arthritis & Rheumatism

TAp63: A new protein drug target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX). Many ...

Immunology

Understanding immunological memory

Humans encounter innumerable pathogenic bacteria, viruses and other microbes in their day-to-day activities. While infections from some pathogens can be easily cleared by the innate immune system, others can evade this first ...

Immunology

Engineered bacteria find tumors, then alert immune cells

Combining discoveries in cancer immunology with sophisticated genetic engineering, Columbia University researchers have created a sort of "bacterial suicide squad" that targets tumors, attracting the host's own immune cells ...

Oncology & Cancer

Boosting anti-cancer antibodies by reducing their grip

New research from the Centre for Cancer Immunology at the University of Southampton, published ahead of World Cancer Day (February 4), has shown that changing how tightly an antibody binds to a target could improve treatments ...

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