Oncology & Cancer

Drug shows promise as immune therapy for cancer

A therapy developed by Yale researchers stimulates immune cells to shrink or kill tumors in mice, according to a new study published in the Journal of Experimental Medicine. The therapy is effective alone or in combination ...

Immunology

Researchers unravel the early makings of an exhausted T cell

The immune system struggles to defeat cancer or chronic infections because many of the T cells that leap into action end up "exhausted," rendering them ineffective against disease. That path to exhaustion and what triggers ...

Immunology

When studying immune cells, environment matters

For years, scientists have used cells grown in petri dishes to study the metabolic processes that fuel the immune system. But a new report in Immunity suggests looking outside the dish and into living organisms gives a drastically ...

Diseases, Conditions, Syndromes

Researchers identify new therapeutic target for pulmonary fibrosis

Researchers in Japan have identified a genetic mutation that causes a severe lung disease called idiopathic pulmonary fibrosis (IPF) by killing the cells lining the lung's airways. The study, which will be published October ...

Diseases, Conditions, Syndromes

How nasty Toxoplasma parasite damages the human eye

One-third of the world population is infected with Toxoplasma, which causes a common eye infection called ocular toxoplasmosis. Researchers have shed new light on how an infection with the parasite causes a distinctive lesion ...

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