Inflammatory disorders

Hibernating control cells or why inflammations become chronic

Rheumatoid arthritis is the most common autoimmune disease of the joints. It causes a chronic inflammatory response, with the body's own immune cells attacking the joint, including the cartilage and bone. This process does ...

Immunology

Scientists unearth cell 'checkpoint' that stops allergic diseases

Scientists from Trinity College Dublin have made a significant breakthrough in understanding the regulation of immune cells that play a pivotal role in allergic diseases such as asthma and eczema. They have identified a 'checkpoint' ...

Immunology

Study pinpoints key pathway in inflammation and aging

In patients with colitis, a serious condition affecting the gut, the immune system turns against the body's own microbes, causing inflammation. To combat this inflammation, scientists have focused in on a chemical signal ...

Inflammatory disorders

Study offers new insight into powerful inflammatory regulator

A new study in mice reveals how a protein called Brd4 boosts the inflammatory response—for better and for worse, depending on the ailment. The study is the first to show that this protein, while problematic in some circumstances, ...

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