There have been great expectations regarding the production of a drug to block the enzyme LTA4 hydrolase, which plays a key role in the body's inflammatory response. However, in clinical trials, such molecules have proven ...
Mar 3, 2014
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A well-documented suppressor of immunity that's used by fetuses and tumors alike, just may be able to change its spots, researchers report.
Jan 7, 2014
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Saint Louis University researchers have analyzed the microbiomes of people with chronic rhinosinusitis and healthy volunteers and found evidence that some chronic sinus issues may be the result of inflammation triggered by ...
Dec 19, 2013
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(Medical Xpress)—A head injury can lead immune-system brain cells to go on "high alert" and overreact to later immune challenges by becoming excessively inflammatory – a condition linked with depressive complications, ...
Dec 9, 2013
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A new research discovery published in the December 2013 issue of the Journal of Leukocyte Biology yields an important clue toward helping curb runaway inflammation. Oxygen levels play a critical role in determining the severity ...
Dec 2, 2013
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Depending on the signals received, naïve T cells are able to differentiate into mature T cell populations, which play different roles in the immune system. For example, regulatory T cells (Tregs) are important for tamping ...
Nov 25, 2013
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Chronic inflammation has long been known as a key risk factor for cancer—-particularly colon cancer—-but the exact mechanisms of how inflammation heightens the immune response, and ultimately influences the initiation ...
Nov 11, 2013
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Research led by Charles Nichols, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, describes a powerful new anti-inflammatory mechanism that could lead to the development of new oral medications ...
Oct 3, 2013
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The c-Fos oncogene has traditionally been linked to cellular activities related to cancer, such as cell division, differentiation—conversion from one cell type to another—or survival. Any alteration of these activities ...
Sep 27, 2013
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(Medical Xpress)—Scientists have identified a process associated with inflammation in cancer that they believe could lead to expanded treatment options for some types of ovarian tumours.
Sep 26, 2013
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