Removing a nuclear bile acid receptor that regulates glucose and lipid stability from the intestine blocks gut inflammation in mice, according to researchers at Children's Hospital Los Angeles. Their findings are published ...
13 hours ago
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Endometriosis is a disease in which tissue similar to what lines the uterus grows outside of it. The disease, which affects 10% of women of reproductive age worldwide, causes severe pain and often infertility. Many of the ...
Aug 14, 2024
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The wellness industry has brought gut health to the forefront, and for good reason. Our digestive system's condition affects various aspects of our well-being, from mood to skin health. While bloating is a well-known sign ...
Aug 13, 2024
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A new study from scientists at Cincinnati Children's suggests there may be a way to further protect transplanted hearts from rejection by preparing the donor organ and the recipient with an anti-inflammatory antibody treatment ...
Aug 12, 2024
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Periodontitis is initiated by dysbiosis of the oral microbiome. Pathogenic bacteria elicit ineffective immune responses, which damage surrounding tissues and lead to chronic inflammation. Although current treatments typically ...
Aug 8, 2024
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Nearly a quarter of children with recurrent wheezing have "silent" lung infections that would be better treated with antiviral medications than commonly prescribed steroids that can carry lifelong side effects, new research ...
Aug 6, 2024
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Millions of people worldwide suffer from liver inflammation (hepatitis), an acute or chronic disease with a variety of causes. Liver inflammation frequently occurs in connection with metabolic disorders, for example fatty ...
Aug 6, 2024
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Known for their role in allergic reactions, mast cells have long been recognized as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue ...
Aug 2, 2024
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University of Virginia School of Medicine researchers have identified a potential treatment for the respiratory symptoms of long COVID after discovering an unknown cause of the condition inside the lungs.
Jul 30, 2024
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The processes in the brain and body through which physical exercise reduces depressive symptoms have been explored by UCL researchers.
Jul 29, 2024
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Inflammation (Latin, inflamatio, to set on fire) is the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue. Inflammation is not a synonym for infection. Even in cases where inflammation is caused by infection, the two are not synonymous: infection is caused by an exogenous pathogen, while inflammation is the response of the organism to the pathogen.
In the absence of inflammation, wounds and infections would never heal and progressive destruction of the tissue would compromise the survival of the organism. However, an inflammation that runs unchecked can also lead to a host of diseases, such as hay fever, atherosclerosis, and rheumatoid arthritis. It is for that reason that inflammation is normally closely regulated by the body.
Inflammation can be classified as either acute or chronic. Acute inflammation is the initial response of the body to harmful stimuli and is achieved by the increased movement of plasma and leukocytes from the blood into the injured tissues. A cascade of biochemical events propagates and matures the inflammatory response, involving the local vascular system, the immune system, and various cells within the injured tissue. Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells which are present at the site of inflammation and is characterised by simultaneous destruction and healing of the tissue from the inflammatory process.
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