Immunology

Molecular component of caffeine may play a role in gut health

Brigham researchers studying how and why certain cell types proliferate in the gut found that xanthine, which is found in coffee, tea and chocolate, may play a role in Th17 differentiation. Insights may help investigators ...

Medical research

How gut microbes help mend damaged muscles

The human immune system is incredibly versatile. Among its most skilled multitaskers are T cells, known for their role in everything from fighting infection to reining in inflammation to killing nascent tumors.

Immunology

Psoriasis tied to elevated risk for celiac disease

Individuals with psoriasis have double the odds of having celiac disease (CD) versus individuals without psoriasis, according to a research letter published online Feb. 9 in the Journal of the American Academy of Dermatology.

Gastroenterology

Your gut's microbiome, on a chip

The gut is one of the most complex organs in the body. Inside, it teems with a diverse microbial population that interacts and cooperates with intestinal cells to digest food and drugs. Disruptions in this microbiome have ...

Oncology & Cancer

Identifying the inflammatory cells behind chemo brain

Immune cells that keep the brain free of debris but also contribute to inflammation are the likely culprits behind the concentration and memory problems that sometimes follow one type of chemotherapy, a new study in mice ...

Medical research

Q&A: Why you should publish negative data

As a bachelor student of Bio-Pharmaceutical Sciences, Femke Vlaswinkel wrote a research proposal she was allowed to carry out in her master's BPS. Femke subsequently graduated with honors. Her research was published in the ...

Immunology

Testing their strength: CAR T-cells combat muscle inflammation

Universitätsklinikum Erlangen is the first in the world to use CAR T-cells to successfully treat a patient suffering from a severe case of muscle inflammation (myositis). The disease is triggered by a malfunction in the ...

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