Genetics

A human interactome to prioritize drug discovery

Scientists at Open Targets, EMBL's European Bioinformatics Institute (EMBL-EBI), and GSK are revealing the shared basis of diseases using a map of interacting human proteins. By helping to understand how biological processes ...

Immunology

Testing their strength: CAR T-cells combat muscle inflammation

Universitätsklinikum Erlangen is the first in the world to use CAR T-cells to successfully treat a patient suffering from a severe case of muscle inflammation (myositis). The disease is triggered by a malfunction in the ...

Dentistry

Gum inflammation parallels novel 'cytokine score'

Researchers at NYU College of Dentistry have developed a single score to describe the level of cytokines in saliva, and this score is linked with the severity of clinical gum inflammation, according to a study published in ...

Gastroenterology

Creating organoids with immune systems

In many ways, our intestines serve as the front gate between our bodies and the world around us. They help digest our food and absorb our medications. They send alarm signals when harmful bacteria, viruses, and allergens ...

Neuroscience

Researchers map brain cell changes in Alzheimer's disease

A common sign of Alzheimer's disease is the excessive buildup of two types of protein in the brain: tangles of tau proteins that accumulate inside cells, and amyloid-β proteins that form plaques outside the cells. Researchers ...

Cardiology

Why arteriosclerosis looks like an autoimmune disease

Arteriosclerosis bears great similarities to autoimmune diseases. Researchers from Leiden University show this in a new study they published in the journal Nature Cardiovascular Research. "This discovery suggests that treatment ...

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