Immunology

Cell death protein could offer new anti-inflammatory drug target

Scientists in Melbourne, Australia, have revealed the structure of a protein that is essential for triggering a form of programmed cell death, making possible the development of new drugs to treat chronic inflammatory diseases ...

Arthritis & Rheumatism

Rheumatoid arthritis: Biologics in second-line therapy show benefit

The German Institute for Quality and Efficiency in Health Care (IQWiG) examined 9 biotechnologically produced drugs for the treatment of adults with rheumatoid arthritis in whom prior pharmacological treatment had failed. ...

Parkinson's & Movement disorders

Brain inflammation linked to more severe Parkinson's symptoms

Reversing inflammation in the fluid surrounding the brain's cortex may provide a solution to the complex riddle of Parkinson's, according to researchers who have found a link between pro-inflammatory biomarkers and the severity ...

Diseases, Conditions, Syndromes

Opening up new pathways for treating inflammatory bowel diseases

Inflammatory bowel disease (IBD) is a chronic condition affecting 1 in 250 people in Europe. Current treatment is ineffective for many. However, a team of European scientists has increased understanding of the causes of IBD, ...

Diabetes

Drug preserves beta cells in new cases of type 1 diabetes

(Medical Xpress)—A drug in clinical trials has been shown to preserve insulin-producing pancreatic beta cells in nearly half of subjects newly diagnosed with type 1 diabetes. Results of the phase 2 trials are published ...

Diseases, Conditions, Syndromes

Sex differences in kidney gene expression

Male and female rats show different patterns of kidney gene expression throughout their lives, a study in the open access journal Biology of Sex Differences reveals. The finding could help explain some of the gender differences ...

Diseases, Conditions, Syndromes

Study suggests worsening trends in back pain management

Patient care could be enhanced and the health care system could see significant cost savings if health care professionals followed published clinical guidelines to manage and treat back pain, according to researchers at Beth ...

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