Medical research

Team develops a sugary-sweet new method for biomarker discovery

Everyone loves a sweet treat, even our cells. While we typically think of sugar as a component of our diet that gives us energy, sugars are also very important in guiding the activity of our cells. Sugar molecules can be ...

Neuroscience

How heavy alcohol consumption increases brain inflammation

For people with alcohol use disorder (AUD), there is a constant, vicious cycle between changes to the brain and changes to behavior. AUD can alter signaling pathways in the brain; in turn, those changes can exacerbate drinking.

Arthritis & Rheumatism

Study identifies key protein that drives rheumatoid arthritis damage

Scientists have identified a protein known as sulfatase-2 that plays a critical role in the damage caused by rheumatoid arthritis. A chronic disease in which the immune system attacks the body's own joint tissues, rheumatoid ...

Medical research

'Growing end' of inflammation discovered

Redness, swelling and pain are signs of inflammation. It serves to protect the body from pathogens and foreign substances. Researchers from the Universities of Bonn and Cologne were able to show that inflammatory reactions ...

Inflammatory disorders

Structure of central inflammation switch elucidated

Researchers at the Universities of Bonn and Regensburg have elucidated the structure of a central cellular inflammatory switch. Their work shows which site of the giant protein called NLRP3 inhibitors can bind to. This opens ...

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