Inflammatory disorders

Structure of central inflammation switch elucidated

Researchers at the Universities of Bonn and Regensburg have elucidated the structure of a central cellular inflammatory switch. Their work shows which site of the giant protein called NLRP3 inhibitors can bind to. This opens ...

Diseases, Conditions, Syndromes

Investigating the modulation of the COVID-19 immune response

In a recent paper, the research team around Prof. Antonio del Sol from the University's Luxembourg Centre for Systems Biomedicine (LCSB) describes a new method of how molecules can be identified that amplify and maintain ...

Overweight & Obesity

Blood vessel cells implicated in chronic inflammation of obesity

Dec. 30, 2020—When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with ...

Vaccination

New vaccine design reduces inflammation, enhances protection

Adjuvants are a key ingredient of many modern vaccines, working to unleash an immune response that helps protect the body from disease. Many scientists believe that adjuvants are they key to developing new kinds of vaccines ...

Immunology

The yin and yang of inflammation controlled by a single molecule

Researchers from the Perelman School of Medicine at the University of Pennsylvania have now identified a protein called histone deacetylase 3 (HDAC3) as the orchestrator of the immune system's inflammation response to infection. ...

Medical research

How resident microbes restructure body chemistry

The makeup of our microbiomes—the unique communities of bacteria, viruses and other microbes that live in and on us—have been linked, with varying degrees of evidence, to everything from inflammatory bowel disease to ...

Diseases, Conditions, Syndromes

Fungi cause brain infection and impair memory in mice

Fungal infections are emerging as a major medical challenge, and a team led by researchers at Baylor College of Medicine has developed a mouse model to study the short-term consequences of fungal infection in the brain.

Immunology

Cannabis link to relieving intestinal inflammation explained

Reports from cannabis users that the drug reduces the symptoms of inflammatory bowel disease (IBD) may finally be explained by new research from the University of Massachusetts Medical School and the University of Bath showing ...

page 2 from 9