Neuroscience

Being hungry shuts off perception of chronic pain

Pain can be valuable. Without it, we might let our hand linger on a hot stove, for example. But longer-lasting pain, such as the inflammatory pain that can arise after injury, can be debilitating and costly, preventing us ...

Genetics

Researchers explore epigenetic influences of chronic pain

Chronic pain is one of the most prevalent, disabling and expensive public health crises in the United States. It affects more than 100 million Americans, with annual costs estimated at $635 billion, says a 2014 report from ...

Inflammatory disorders

New drug promises relief for inflammatory pain

Pain from inflammation sidelines thousands of Americans each year. Many face a tough choice: deal with the pain, take a potentially addictive opioid or use a nonsteroidal anti-inflammatory drug that may increase risk for ...

Neuroscience

Researchers find new target for chronic pain treatment

Researchers at the UNC School of Medicine have found a new target for treating chronic pain: an enzyme called PIP5K1C. In a paper published today in the journal Neuron, a team of researchers led by Mark Zylka, PhD, Associate ...

Medical research

Plant used in Chinese medicine fights chronic pain

A plant used for centuries as a pain reliever in Chinese medicine may be just what the doctor ordered, especially when it comes to chronic pain. A key pain-relieving ingredient is a compound known as dehydrocorybulbine (DHCB) ...

Medical research

New research finds cause of morphine side effects

A University of Colorado Boulder-led research team has discovered that two protein receptors in the central nervous system team up to respond to morphine and cause unwanted neuroinflammation, a finding with implications for ...

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