Inflammatory diseases like rheumatoid arthritis have complex disease mechanisms that can differ from patient to patient with the same diagnosis. This means that currently available drugs have little effect on many patients. ...
Feb 28, 2023
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Scientists at Open Targets, EMBL's European Bioinformatics Institute (EMBL-EBI), and GSK are revealing the shared basis of diseases using a map of interacting human proteins. By helping to understand how biological processes ...
Feb 23, 2023
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Researchers from the D'Or Institute for Research and Education (IDOR) have just published a study in Translational Psychiatry that elucidates the mechanisms involved in the cognitive deficits of human aging. The research ...
Oct 12, 2022
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A research study published in Immunity has found that the previously identified disease-associated microglia (DAM) population detected in murine Alzheimer's disease models actually contained an additional population of macrophages ...
Oct 12, 2022
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Neurological diseases often begin with an inflammatory process and the degradation of the myelin layer, which surrounds the nerve fibers (axons) like a protective insulating layer. This is usually followed by damage to the ...
Sep 28, 2022
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Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body's white blood cells to go on ...
Jun 2, 2022
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The loss of muscle mass and strength during aging is called sarcopenia. Affecting the elderly population, sarcopenia is a degenerative process that brings about a decrease in wellbeing and increased dependency. A growing ...
Mar 22, 2022
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Inflammatory processes are associated with a large range of human diseases, including rheumatic diseases and allergies. Protein biomarkers are measurable molecules that can have a prognostic value in patients, be used to ...
Dec 8, 2021
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New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) shows that inflammatory reactions can be resolved by changes to the metabolism of macrophages. Danger signals released by damaged ...
Nov 8, 2021
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A protein that provides essential protection against free radicals inside the cell provokes damaging inflammation when released outside, activating immune cells and worsening damage following a stroke, according to a new ...
May 20, 2021
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