Arthritis & Rheumatism

JAK signaling may be behind polymyalgia rheumatica

Janus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study published online June 29 in PLOS Medicine.

Immunology

New study gives clues on why exercise helps with inflammation

Researchers have long known that moderate exercise has a beneficial impact on the body's response to inflammation, but what's been less understood is why. New research coming out of York University done on a mouse model suggests ...

Immunology

Immune cell movement worse in older females, mice study finds

According to a new study, older female mice had more immune cells entering areas of the body where they should not have, demonstrating that sex differences contribute to age-related inflammation, which should be considered ...

Genetics

Researchers target protein that can slow down muscular dystrophy

A team of researchers at the University of Houston College of Pharmacy is reporting that by manipulating TAK1, a signaling protein that plays an important role in development of the immune system, they can slow down disease ...

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