Oncology & Cancer

Researchers find BRAF protein modification could slow tumor growth

The protein BRAF is a key player in the development of many different types of cancer, including melanoma. Scientists have known that BRAF becomes activated by growth factors and subsequently stimulates downstream proteins ...

Neuroscience

Inflammation signals induce dormancy in aging brain stem cells

In old age, the amount of stem cells in the brains of mice decreases drastically. The remaining ones protect themselves from completely vanishing by entering a state of dormancy, scientists from the German Cancer Research ...

Psychology & Psychiatry

What happens to your body when you're stressed

We all feel stressed from time to time – it's all part of the emotional ups and downs of life. Stress has many sources, it can come from our environment, from our bodies, or our own thoughts and how we view the world around ...

Immunology

Study pinpoints key pathway in inflammation and aging

In patients with colitis, a serious condition affecting the gut, the immune system turns against the body's own microbes, causing inflammation. To combat this inflammation, scientists have focused in on a chemical signal ...

Neuroscience

Optical control of a neuroreceptor alleviates chronic pain

Pain serves as a valuable warning signal, but when it becomes chronic, pain should be considered as a real disease. An international team including research scientists from the CNRS and INSERM1 has identified and controlled ...

Inflammatory disorders

New drug target for inflammatory disease is all the RAGE

Researchers have shown that Receptor for Advanced Glycation End Products (RAGE) helps to regulate a key signaling pathway known to promote both acute and chronic inflammation. The development of therapeutic drugs targeted ...

Immunology

Targeting the gut-brain connection can impact immunity

There's a reason it's called a gut feeling. The brain and the gut are connected by intricate neural networks that signal hunger and satiety, love and fear, even safety and danger. These networks employ myriad chemical signals ...

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