A naturally occurring peptide called PEPITEM could potentially rejuvenate the immune response in older individuals and protect against "inflammaging," which is widely believed to be the root cause of many age-related diseases.
Jul 18, 2024
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In patients with colitis, a serious condition affecting the gut, the immune system turns against the body's own microbes, causing inflammation. To combat this inflammation, scientists have focused in on a chemical signal ...
May 9, 2017
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In old age, the amount of stem cells in the brains of mice decreases drastically. The remaining ones protect themselves from completely vanishing by entering a state of dormancy, scientists from the German Cancer Research ...
Feb 28, 2019
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A new research paper has been published in Aging (Aging-US), titled "Effect of Humanin G (HNG) on inflammation in age-related macular degeneration (AMD)."
May 31, 2022
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A University of Louisville scientist has found a way to prevent inflammation and bone loss surrounding the teeth by blocking a natural signaling pathway of the enzyme GSK3b, which plays an important role in directing the ...
Sep 11, 2012
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When the bacterium Helicobacter pylori infects the stomach, it causes gastric inflammation and increases the risk of stomach cancer. A team of researchers from Charité—Universitätsmedizin Berlin and the Max Delbrück ...
Apr 20, 2022
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University of Louisville researchers have replicated the inflammatory gene changes of a human kidney as it progresses from mild to severe diabetic nephropathy, using a mouse model developed by a UofL researcher, according ...
May 23, 2011
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A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.
Aug 3, 2023
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A new study unravels key signals that regulate protective and sometimes pathological inflammation of the skin. The research, published online on January 26th in the journal Immunity by Cell Press, identifies a "gatekeeper" ...
Jan 26, 2012
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Mutations in the enzyme IDH (isocitrate dehydrogenase) are found in 15–20% of acute myeloid leukemia (AML) cases. IDH mutations have been shown to impact cellular differentiation and DNA and histone methylation, but little ...
Dec 13, 2021
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