Immunology

First flu exposure imprints itself on immune system

A person's first infection with the influenza virus likely stimulates the production of key antibodies that then shape later immune responses to different seasonal influenza strains. In a study published December 17th in ...

Diseases, Conditions, Syndromes

Prime-boost H7N9 influenza vaccine concept promising in clinical trial

In clinical trials, several candidate H7N9 pandemic influenza vaccines made from inactivated viruses have been shown to be safe and to generate an immune response. However, scientists believe for practical use, these potential ...

Immunology

Researchers identify essential component of antiviral defense

Infectious disease researchers at the University of Georgia have identified a signaling protein critical for host defense against influenza infection. The findings, recently published in PLoS Pathogens, shed light on how ...

Medical research

Cause of viral infection of the brain mapped out

Researchers from Aarhus University and Aarhus University Hospital have - in collaboration with international researchers - found a cause for why contracting herpes virus ends up being fatal for some people. While most people ...

Immunology

Flu infection reveals many paths to immune response

A new study of influenza infection in an animal model broadens understanding of how the immune system responds to flu virus, showing that the process is more dynamic than usually described, engaging a broader array of biological ...

Immunology

'Immune Camouflage' may explain H7N9 influenza vaccine failure

The avian influenza A (H7N9) virus has been a major concern since the first outbreak in China in 2013. Due to its high rate of lethality and pandemic potential, H7N9 vaccine development has become a priority for public health ...

Medications

Adjuvants improve immune response to H7N9 flu vaccine

In a phase 2 trial that included nearly 1,000 adults, the AS03 and MF59 adjuvants (a component that improves immune response of inactivated influenza vaccines) increased the immune responses to two doses of an inactivated ...

Immunology

Drug target for asthma discovered

The over-active immune cells responsible for asthma depend on the gene BCL11B to develop into mature cells, according to a study published in the Journal of Experimental Medicine. The identification of this gene's role could ...

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