Diseases, Conditions, Syndromes

Study highlights RSV burden on infants in Nicaragua

Respiratory syncytial virus, a major cause of lower respiratory tract infections, is behind one of every four deaths from acute illness for children under 2 years old in Nicaragua, according to a new University of Michigan ...

Diseases, Conditions, Syndromes

Infectious disease A-Z: Will there be a universal flu vaccine?

A better, more effective flu vaccine is a matter of when—not if—says Dr. Gregory Poland, director of Mayo Clinic's Vaccine Research Group. The National Institutes of Health is testing an experimental universal flu vaccine ...

Medical research

Mapping the structure of the influenza A virus genome

A team of researchers from the U.K., Australia and the U.S. has mapped the structure of the influenza A virus genome. In their paper published in the journal Nature Microbiology, the group describes their genetic analysis ...

Medical research

Gut microbes protect against flu virus infection in mice

Commensal gut microbes stimulate antiviral signals in non-immune lung cells to protect against the flu virus during early stages of infection, researchers report July 2nd in the journal Cell Reports. Enhanced baseline type ...

Diseases, Conditions, Syndromes

You can't get influenza from a flu shot

Influenza is a moving target for vaccines. Each year, up to four different strains circulate, and they are constantly evolving to escape our immune system.

Diseases, Conditions, Syndromes

2018 to 2019 influenza season in U.S. was longest in 10 years

In the United States, the 2018 to 2019 influenza season was of moderate severity and lasted 21 weeks, according to research published in the June 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and ...

Diseases, Conditions, Syndromes

Sick with the flu? Here's why you feel so bad

"You never forget the flu." This is the title of the Victorian health department's current campaign, which highlights people's recollections of having the flu.

Medical research

Deadly tick-borne virus cured with experimental flu drug, in mice

Only a few cases of the newly discovered Bourbon virus have been reported, and two of them ended in death, partly because no specific treatments are available for the tick-borne illness. Now, researchers at Washington University ...

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Orthomyxoviridae

Influenzavirus A Influenzavirus B Influenzavirus C Isavirus Thogotovirus

The Orthomyxoviridae (orthos, Greek for "straight"; myxa, Greek for "mucus") are a family of RNA viruses that includes five genera: Influenzavirus A, Influenzavirus B, Influenzavirus C, Isavirus and Thogotovirus. The first three genera contain viruses that cause influenza in vertebrates, including birds (see also avian influenza), humans, and other mammals. Isaviruses infect salmon; thogotoviruses infect vertebrates and invertebrates, such as mosquitoes and sea lice.

The three genera of Influenzavirus, which are identified by antigenic differences in their nucleoprotein and matrix protein infect vertebrates as follows:

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