A new weakness has been discovered in cancer cells that may make them more susceptible to chemotherapy and other treatments. In a research report appearing in the September 2013 issue of The FASEB Journal, scientists identify ...
Aug 29, 2013
0
0
Researchers at Moffitt Cancer Center and colleagues have demonstrated that the inhibition of signal transducer and activator of transcription 3 (STAT3) in mouse models of mantle cell lymphoma (MCL), an aggressive and incurable ...
Jul 18, 2012
0
0
Patients with HER2-positive breast cancer being treated with anti-HER2 therapy may be able to prevent or delay resistance to the therapy with the addition of a phosphatidylinositol-3 kinase inhibitor to their treatment regimens.
Jan 23, 2013
0
0
A Brazilian study shows that inhibition of an RNA named RMEL3, which is encoded by a previously uncharacterized gene (also named RMEL3), can reduce the viability of cultured melanoma cells by up to 95%.
Aug 4, 2016
0
2
The third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) osimertinib is effective in the first-line treatment of EGFR mutated non-small-cell lung cancer (NSCLC), according to a late-breaking ...
Apr 14, 2016
0
0
(HealthDay)—A case of acquired resistance to crizotinib has been described in a patient with metastatic lung adenocarcinoma harboring a CD74-ROS1 rearrangement, according to a brief report published online June 1 in the ...
Jun 3, 2013
0
0
The strongest epidemiological risk factor for many forms of pulmonary arterial hypertension (PAH) is female gender. Increased estrogen makes females three times more likely to develop PAH, a chronic disease that eventually ...
Aug 18, 2017
0
0
The human immune system has a natural ability to identify and attack tumor cells. Natural killer (NK) cells are innate immune cells that are particularly effective at killing tumor cells due to their ability to secrete cytotoxic ...
Jun 11, 2012
0
1
Obesity is linked to the widespread epidemics of diabetes and heart disease that plague society, but a lesser-known fact is that the weight can also lead to autoimmune disease. Now, researchers have new information about ...
Apr 4, 2013
0
0
Among patients with heart failure with preserved ejection fraction (a measure of heart function), administration of sildenafil (commercially known as Viagra) for 24 weeks, compared with placebo, did not result in significant ...
Mar 11, 2013
0
0
