Oncology & Cancer

Priming the immune system to attack cancer

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, ...

Immunology

Innate lymphoid cells regenerate within lung

The immune system is equipped with numerous cell types that effectively fight the various pathogens, humans can encounter during their lives. T cells, for example, have a receptor through which they can specifically recognize ...

Diseases, Conditions, Syndromes

Early immune response may contribute to severe COVID-19

Researchers may have come one step closer toward understanding how the immune system contributes to severe COVID-19. In a study published in Science Immunology, researchers at Karolinska Institutet in Sweden show that so-called ...

Immunology

TLK protein inhibition activates the innate immune system

Tousled-like kinases (TLKs) are a potential therapeutic target for cancer treatment due to their central role in DNA repair and replication. The latest work by IRB Barcelona's Genomic Instability and Cancer Laboratory, led ...

Medical research

A bacterial toxin turning cells into swiss cheese

Although the innate immune system is the front line of defense against microbial infections, the complex mechanisms of innate immunity are incompletely understood. In a new study, researchers from Kanazawa University synthesized ...

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Innate immune system

The innate immune system comprises the cells and mechanisms that defend the host from infection by other organisms, in a non-specific manner. This means that the cells of the innate system recognize and respond to pathogens in a generic way, but unlike the adaptive immune system, it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life.

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