Researchers at Radboudumc have unveiled a fascinating connection between sphingolipids, mysterious fats named after the "Sphinx," and the memory of cells from the innate immune system. This discovery provides new avenues ...
Nov 28, 2023
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Human cytomegalovirus (HCMV) is a β-herpesvirus that infects most of the world's population and poses a serious threat to human health. The constant exposure of HCMV to the innate immune system makes this virus evolve a ...
Oct 9, 2023
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Severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, according to a small study. These changes may help explain why the disease can damage so many different ...
Aug 18, 2023
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By the time multiple sclerosis is normally diagnosed—when brain lesions appear on magnetic resonance imaging scans—the patient can have irreversible damage and treatment options can be limited. But in a Stanford Medicine-led ...
Aug 8, 2023
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Respiratory viruses like influenza virus (flu), SARS-CoV-2 (which causes COVID) and respiratory syncytial virus (RSV) can make us sick by infecting our respiratory system, including the nose, upper airways and lungs.
Jul 30, 2023
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A team led by researchers at Massachusetts General Hospital (MGH) has discovered a protein that plays critical roles in alerting the body to a bacterial infection and initiating an effective immune response to fight back ...
Jul 26, 2023
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Questions abound when it comes to the molecular mechanisms deployed by the human immune system to thwart cancer and infection, and questions especially abound when it comes to the precise steps taken by the innate immune ...
Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body's important inflammatory responses. Their findings, published in the journal Science Immunology, open ...
Jun 16, 2023
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Humans encounter innumerable pathogenic bacteria, viruses and other microbes in their day-to-day activities. While infections from some pathogens can be easily cleared by the innate immune system, others can evade this first ...
May 11, 2023
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Researchers from Karolinska Institutet and Sachs' Children and Youth Hospital have mapped the immune system in the gut of children with inflammatory bowel disease (IBD). The results, which were published in Cell Reports Medicine, ...
May 9, 2023
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The innate immune system comprises the cells and mechanisms that defend the host from infection by other organisms, in a non-specific manner. This means that the cells of the innate system recognize and respond to pathogens in a generic way, but unlike the adaptive immune system, it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life.
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