Researchers from Children's Hospital of Philadelphia (CHOP) revealed the mechanisms behind one particular molecule's involvement in regulating insulin sensitivity. The findings, which were translated from a preclinical animal ...
Jun 28, 2024
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Bisphenol A (BPA) administration is associated with reduced peripheral insulin sensitivity among healthy adults, according to a study presented at the annual meeting of the American Diabetes Association, held from June 21 ...
Jun 27, 2024
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A common plastic chemical might increase a person's risk of diabetes, a new study warns.
Jun 26, 2024
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High insulin levels contribute to worse outcomes for Black women compared to white women who have an aggressive form of breast cancer called triple-negative breast cancer, according to a study presented at ENDO 2024, the ...
Jun 3, 2024
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In a recent study, the Leibniz Institute for Prevention Research and Epidemiology—BIPS has made significant progress in identifying health markers that are crucial for a long and healthy life. Led by Prof. Dr. Krasimira ...
May 29, 2024
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University of Oklahoma researchers have deepened their understanding of a drug's ability to prevent fat buildup in the liver, a condition that often occurs with obesity and can lead to serious fatty liver disease. Their findings—which ...
May 23, 2024
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For years, people have used intermittent fasting to lose unwanted pounds, while others fast for religious reasons. The popular diet trend is generally safe, but some studies suggest that time-restricted eating could cause ...
May 23, 2024
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An active lifestyle can change how the body burns saturated and unsaturated fat according to new research from the University of Aberdeen.
May 16, 2024
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People have a pretty intuitive sense of what is healthy—standing is better than sitting, exercise is great for overall health and getting good sleep is imperative.
May 2, 2024
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What happens in the body when we are hungry and see and smell food? A team of researchers at the Max Planck Institute for Metabolism Research has now been able to show in mice that adaptations in the liver mitochondria take ...
Apr 25, 2024
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Insulin resistance (IR) is the condition in which normal amounts of insulin are inadequate to produce a normal insulin response from fat, muscle and liver cells. Insulin resistance in fat cells reduces the effects of insulin and results in elevated hydrolysis of stored triglycerides in the absence of measures which either increase insulin sensitivity or which provide additional insulin. Increased mobilization of stored lipids in these cells elevates free fatty acids in the blood plasma. Insulin resistance in muscle cells reduces glucose uptake (and so local storage of glucose as glycogen), whereas insulin resistance in liver cells results in impaired glycogen synthesis and a failure to suppress glucose production. Elevated blood fatty acid levels (associated with insulin resistance and diabetes mellitus Type 2), reduced muscle glucose uptake, and increased liver glucose production all contribute to elevated blood glucose levels. High plasma levels of insulin and glucose due to insulin resistance are believed to be the origin of metabolic syndrome and type 2 diabetes, including its complications.
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