Health

When you eat may matter more than what you eat: study

(HealthDay)—There's evidence that the old expression "eat breakfast like a king, lunch like a prince and dinner like a pauper" could use some tweaking. With one important revision, this approach could help not just for ...

Diabetes

Intermittent fasting protects mice from type 2 diabetes

Every-other-day fasting substantially reduces the likelihood of developing type 2 diabetes in mice eating a fat-rich diet, according to new research out of the German Institute of Human Nutrition Potsdam-Rehbruecke. These ...

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Insulin resistance

Insulin resistance (IR) is the condition in which normal amounts of insulin are inadequate to produce a normal insulin response from fat, muscle and liver cells. Insulin resistance in fat cells reduces the effects of insulin and results in elevated hydrolysis of stored triglycerides in the absence of measures which either increase insulin sensitivity or which provide additional insulin. Increased mobilization of stored lipids in these cells elevates free fatty acids in the blood plasma. Insulin resistance in muscle cells reduces glucose uptake (and so local storage of glucose as glycogen), whereas insulin resistance in liver cells results in impaired glycogen synthesis and a failure to suppress glucose production. Elevated blood fatty acid levels (associated with insulin resistance and diabetes mellitus Type 2), reduced muscle glucose uptake, and increased liver glucose production all contribute to elevated blood glucose levels. High plasma levels of insulin and glucose due to insulin resistance are believed to be the origin of metabolic syndrome and type 2 diabetes, including its complications.

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