Diseases, Conditions, Syndromes

Unpacking the body's interferon response to COVID-19

Interferons are potent natural antivirals, rallying other parts of the immune system to defend against viruses. Some clinical trials have tested interferons as a treatment for COVID-19, but results have been mixed, and the ...

Oncology & Cancer

New cancer findings can give wider access to immunotherapy

Researchers at Karolinska Institutet in Sweden have published new findings in the journal Cancer Discovery showing how pharmacological activation of the protein p53 boosts the immune response against tumours. The results ...

Immunology

Exercising muscle combats chronic inflammation on its own

Biomedical engineers at Duke University have demonstrated that human muscle has an innate ability to ward off the damaging effects of chronic inflammation when exercised. The discovery was made possible through the use of ...

Diseases, Conditions, Syndromes

COVID-19 virus helps block host immunity

SARS-CoV-2, the virus that causes COVID-19, blocks the processes of innate immune activation that normally direct the production and/or signaling of type I interferon (IFN-I) by the infected cell and tissues. IFN-I is a key ...

Diseases, Conditions, Syndromes

Scientists identify 'immune cop' that detects SARS-CoV-2

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified the sensor in human lungs that detects SARS-CoV-2 and signals that it's time to mount an antiviral response. The study, published today in Cell ...

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