(HealthDay)—For patients with hepatitis C virus (HCV) treated with pegylated interferon-alpha and ribavirin (P/R), drinking patterns and the amount of alcohol consumed before treatment do not impact treatment success, according ...
Oct 11, 2012
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Researchers have identified the primary player of the biochemical bugle call that musters the body's defenders against viral infection.
Jun 13, 2012
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SARS-CoV-2, the virus that causes COVID-19, blocks the processes of innate immune activation that normally direct the production and/or signaling of type I interferon (IFN-I) by the infected cell and tissues. IFN-I is a key ...
Jan 21, 2021
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A new study describes how NS1, a protein produced by influenza A viruses, suppresses the body's immune responses to viral infection. Researchers present the potential to develop a live attenuated vaccine based on an engineered ...
Aug 14, 2017
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Interleukin-27 (IL-27), a member of the interleukin family of cytokines that help regulate the immune system, has a mainly anti-inflammatory role in the body, and its dysfunction has been implicated in autoimmune diseases ...
Oct 20, 2014
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Regulation of the human immune system's response to infection involves an elaborate network of complex signaling pathways that turn on and off multiple genes. The emerging importance of long noncoding RNAs and their ability ...
Oct 1, 2014
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Millions of people throughout the world are infected with hepatitis C virus (HCV), which can lead to cirrhosis of the liver and cancer. Directly acting antiviral agents inhibit viral proteins and have been used to successfully ...
Jul 1, 2014
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Following an infection, dysregulation of the immune system can result in a systemic inflammatory response and an often fatal condition called severe sepsis or septic shock. Sepsis is not uncommon, yet its cause and underlying ...
Nov 16, 2012
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A study of burn patients has found that those who suffered the most severe smoke inhalation also had more inflammation and spent more time on ventilators and in intensive care.
Nov 16, 2011
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British researchers have identified specific resistance mutations for two classes of p7 inhibitor, which may explain their lack of effectiveness in clinical trials combined with current standard of care. Study results support ...
Jun 28, 2011
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