Diseases, Conditions, Syndromes

SARS-CoV-2 variants have developed resistance to human interferons

Researchers at the University of Colorado Anschutz Medical Campus have investigated how antiviral proteins called interferons interact with SARS-CoV-2, the cause of COVID-19. The study, published in Proceedings of the National ...

Immunology

Cytokines found to contribute to IgA nephropathy

Some cytokines can enhance the production of aberrantly O-glycosylated IgA1, the main autoantigen in IgA nephropathy. The mechanism behind this observation is described in the Journal of Interferon & Cytokine Research (JICR).

Oncology & Cancer

Improving interferon therapy for blood cancers

[Northwestern Medicine investigators have discovered a novel signaling pathway activated by interferons, a group of immune system proteins, that suppresses the anti-tumor response of interferons in patients with a particular ...

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