Diseases, Conditions, Syndromes

How does fibrosis occur in Crohn's disease?

New research has shown that a protein, known as IL-13, could be the key to the development of fibrosis in Crohn's disease. This breakthrough could help to advance new medicines to treat people suffering with the disease.

Medical research

New signal stabilizes atherosclerotic plaques

Atherosclerosis is an inflammatory disease with accumulation of cholesterol in the vessel walls. The atherosclerotic plaque is built up throughout life and when it ruptures it leads to heart attack or stroke. T cells are ...

Inflammatory disorders

Drug halts organ damage in inflammatory genetic disorder

A new study shows that Kineret (anakinra), a medication approved for the treatment of rheumatoid arthritis, is effective in stopping the progression of organ damage in people with neonatal-onset multisystem inflammatory disease ...

Inflammatory disorders

IL-32 expression upregulated in chronic rhinosinusitis

(HealthDay) -- Interleukin-32 (IL-32) mRNA expression is significantly higher in biopsies obtained from patients with chronic rhinosinusitis (CRS), compared to levels found in biopsies obtained from individuals without the ...

Oncology & Cancer

Metastatic melanoma responds to first-line interleukin-21

(HealthDay)—In the first-line treatment of metastatic melanoma, interleukin-21 (IL-21) shows an overall response rate (ORR) of 22.5 percent and warrants further study, according to research published online Aug. 20 in the ...

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