In patients with familial adenomatous polyposis, a genetic disease predisposing to colon cancer, mutations of the APC gene induce the formation of intestinal polyps, but also reduce immune system activity. In a new study, ...
Apr 14, 2022
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53
Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea. Such pathogens pose significant ...
Apr 8, 2022
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64
A research team at the Montreal Heart Institute and Université de Montréal has shown that genes present in specific intestinal cells protect against the development of inflammatory bowel diseases. Published today in the ...
Nov 12, 2021
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136
A high-fat diet disrupts the biology of the gut's inner lining and its microbial communities—and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the ...
Aug 12, 2021
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Why people suffer from chronic inflammatory bowel diseases (IBD) such as ulcerative colitis is only partially understood. However, it is known that the bacteria of the intestinal flora and dysfunction in the immune system ...
Aug 12, 2021
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613
New research has discovered that common artificial sweeteners can cause previously healthy gut bacteria to become diseased and invade the gut wall, potentially leading to serious health issues.
Jun 25, 2021
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To maximize absorption of nutrients from the diet, the intestinal mucous membrane has a large surface area. However, this also makes it vulnerable to attack from aggressive gut microbes. A new study by Uppsala University ...
Apr 12, 2021
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126
A combination of two substances secreted by the immune system can cure and prevent rotavirus infection, as well as potentially treat other viral infections that target epithelial cells, which cover body surfaces such as skin, ...
Oct 2, 2020
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34
The small intestine is one of the most important interfaces between the environment and our body. It is responsible for nutrient absorption but also forms a barrier against potentially harmful environmental cues. A research ...
May 1, 2020
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231
Intestinal epithelial cells (IECs) are exposed to diverse types of environmental stresses such as bacteria and toxins, but the mechanisms by which epithelial cells sense stress are not well understood. New research by the ...
Sep 25, 2019
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