Inflammatory bowel disease, or IBD, describes Crohn's disease and ulcerative colitis, two chronic diseases that cause inflammation in the intestines. IBD, which affects about 3 million adults in the United States, is an autoimmune ...
Apr 7, 2023
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Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.
Apr 4, 2023
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With a length of around eight meters and its countless finger-shaped protrusions, known as villi, the intestine represents the largest contact surface in the inner of our body that comes in contact with up-taken food.
Jan 23, 2023
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Interleukin (IL)-11 is produced by inflammatory fibroblasts, one of the stromal cells, during acute colitis. Researchers at Toho University Japan found that IL-11 ameliorated acute colitis in mouse models. The IL-11 production ...
Jan 17, 2023
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Chronic inflammatory bowel disease (IBD) are inflammations of the gastrointestinal tract which flare up in phases and are accompanied by bloody bowel movements, diarrhea and severe impairment of the quality of life. IBD patients ...
Nov 1, 2021
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A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory ...
Sep 2, 2021
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Through a complex, self-reinforcing feedback mechanism, colorectal cancer cells make room for their own expansion by driving surrounding healthy intestinal cells to death—while simultaneously fueling their own growth. This ...
Jul 12, 2021
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A team of researchers led by biomedical scientist Declan F. McCole at the University of California, Riverside, has found that the drug tofacitinib, also called Xeljanz and approved by the FDA to treat rheumatoid arthritis ...
Sep 30, 2020
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The intestinal epithelium is the inner layer of the intestinal wall, which separates host tissue from the intestinal microbiota. This layer of cells plays a crucial role in water, electrolyte and nutrient absorption, while ...
Jun 8, 2020
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Throughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells and, although they comprise only a small population of the total cells, they are one of the most important moderators ...
Jun 27, 2019
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