The ability to grow three-dimensional precursors of an organ from stem cells in a Petri dish has brought about a revolution in the field of biomedicine. But exactly what can be researched on such an organoid in vitro? A team ...
Nov 19, 2015
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Working with gut stem cells from humans and mice, scientists from the Johns Hopkins Children's Center and the University of Pittsburgh have successfully grown healthy intestine atop a 3-D scaffold made of a substance used ...
Oct 8, 2015
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Up to 80 percent of people with long-standing type 1 diabetes develop gastrointestinal symptoms—abdominal pain, bloating, nausea, vomiting, diarrhea, constipation and fecal incontinence—that severely diminish quality ...
Oct 1, 2015
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The suckling period (infancy) in mice is critical for epigenetic changes (changes that affect the way genes are expressed) in the development of stem cells in the intestine, potentially affecting intestinal health for life. ...
Sep 29, 2015
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Cancer researchers already know of some oncogenes and other factors that promote the development of colon cancers, but they don't yet have the full picture of how these cancers originate and spread. Now researchers from the ...
Aug 5, 2015
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Recent Weizmann Institute studies are revealing a complex picture of cancer progression in which certain genes that drive tumor growth in the earlier stages get suppressed in later stages - taking a step back to move forward. ...
Jun 30, 2015
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Scientists at St. Jude Children's Research Hospital have discovered how an immune system protein, called AIM2 (Absent in Melanoma 2), plays a role in determining the aggressiveness of colon cancer. They found that AIM2 deficiency ...
Jun 19, 2015
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Adult neural stem cells, which are commonly thought of as having the ability to develop into many type of brain cells, are in reality pre-programmed before birth to make very specific types of neurons, at least in mice, according ...
Jun 18, 2015
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Aging is characterized by a decrease in regenerative capacity and organ maintenance as well as an increasing risk of cancer which coincide with mutations in stem and progenitor cells. In a working paper, researchers of Leibniz ...
Jun 5, 2015
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An international group of researchers has shown that a regulatory protein involved in controlling how cancer spreads through the body also influences the fate of stem cells in the intestine of mice. The results, which are ...
Mar 9, 2015
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