Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.
May 22, 2023
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Developmental biologists have learned a great deal about how the human digestive tract functions through many years of studies involving fish, frogs, and rodents along with detailed explorations of individual human cells. ...
May 4, 2023
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Bacteria have thousands of genes and functions that we, the human host, do not have. For instance, bacteria can help us digest fiber, provide support to our immune systems, and absorb important nutrients. But reaping the ...
Mar 29, 2023
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With a length of around eight meters and its countless finger-shaped protrusions, known as villi, the intestine represents the largest contact surface in the inner of our body that comes in contact with up-taken food.
Jan 23, 2023
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Mount Sinai researchers have published one of the first studies to demonstrate the importance of reactive oxygen species in maintaining stem cell function and preventing inflammation during wound repair, which could provide ...
Oct 3, 2022
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Researchers in China have discovered that inhibiting a protein called the GABAA receptor can protect intestinal stem cells from the toxic effects of chemotherapy and radiotherapy.
Sep 20, 2022
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A team led by Ludwig Lausanne's Tatiana Petrova, Jeremiah Bernier-Latmani and alum Christoph Cisarovsky identified a novel mechanism by which stem cells in intestinal tumors generate new blood vessels and evade anti-angiogenic ...
Sep 20, 2022
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The intestine is very susceptible and is affected by the harsh conditions caused by DNA-altering agents, such as radiation and chemotherapy, during cancer treatment. For example, many patients with tumors in the gastrointestinal ...
Sep 14, 2022
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A new study from the lab of University of Kentucky Markey Cancer Director Mark Evers, M.D., demonstrates the critical role of the hormone neurotensin in cell proliferation and stem cell function in the small intestine.
Oct 7, 2021
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Through a complex, self-reinforcing feedback mechanism, colorectal cancer cells make room for their own expansion by driving surrounding healthy intestinal cells to death—while simultaneously fueling their own growth. This ...
Jul 12, 2021
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