Cells within a tumor are not the same; they may have different genetic mutations and different characteristics during growth and throughout treatment. These differences make treating tumors extremely difficult and often lead ...
May 19, 2015
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A neuro-oncology research team at Dartmouth's Norris Cotton Cancer Center, led by the Director Mark A. Israel, MD with first author Gilbert J. Rahme, PhD, recently identified the transcription factor Id4 as a suppressor of ...
Apr 9, 2015
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The sustained presence in the nucleus of the protein known as Rac1 produces changes in nuclear morphology that are important in several biological processes, including malignant cancer. This is the finding of the research ...
Jan 29, 2015
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In a phase 2 clinical trial, women with small (stage 1), HER2-positive breast tumors who received a combination of lower-intensity chemotherapy and a targeted drug following surgery were highly unlikely to have the cancer ...
Jan 7, 2015
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A study combining tumor cells from patients with breast cancer with a laboratory model of blood vessel lining provides the most compelling evidence so far that a specific trio of cells is required for the spread of breast ...
Nov 25, 2014
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One of the tragic realities of cancer is that the drugs used to treat it are highly toxic and their effectiveness varies unpredictably from patient to patient. However, a new "tumor-in-a-dish" technology is poised to change ...
Oct 28, 2014
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A better survival outcome is associated with low blood levels of squamous cell carcinoma antigen, or absence of tumor invasion either into the space between the lungs and chest wall or into blood vessels of individuals with ...
Oct 24, 2014
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Roughly 50,000 Americans are diagnosed with kidney cancer each year. Most of them have small tumors that doctors discover while screening for other health problems.
Jul 11, 2014
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Okayama University medical researchers seek partners to commercialize their clinically proven non-invasive fluorescence virus-guided capture system of human colorectal circulating tumor cells (CTCs) from blood samples for ...
Jul 10, 2014
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The tumor suppressor p53 does all it can to prevent oncogenes from transforming normal cells into tumor cells by killing defective cells or causing them to become inactive. Sometimes oncogenes manage to initiate tumor development ...
Mar 24, 2014
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