The effectiveness of toxin-neutralizing antibodies is considered to be mediated through the interaction of the variable region of the antibody and the toxin; however, recent studies suggest that the constant region (Fc) of ...
Jan 9, 2014
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Bone homeostasis requires precise balance between deposition of new bone by osteoblasts and resorption of old bone by osteoclasts. Bone diseases, including osteoporosis and rheumatoid arthritis, are the result of increased ...
Dec 9, 2013
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Patients with the autoimmune disease systemic lupus erythematosus (SLE) produce autoantibodies that target can cause damage to multiple organ systems. The host factors that are targeted by autoantibodies produced by SLE patients ...
Nov 25, 2013
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Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer deaths worldwide. Current therapies that target cellular kinases have been effective for some patients: however, many individuals with NSCLS do not ...
Nov 8, 2013
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One of the most devastating side effects of diabetes is kidney failure, and one of the earliest signs of kidney damage is a disruption of the organ's filtering capacity. Diabetes patients who develop kidney failure must go ...
Nov 8, 2013
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Epidemiological methods used during the investigation of fatal injuries makes the results more accurate, and allows for greater legal certainty of conclusions. Michael Freeman will address this as he defends his thesis at ...
Nov 6, 2013
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Vitamin D deficiency has been associated with kidney disease including fibrosis. Some studies have even suggested that treatment with vitamin D or vitamin D analogs can reduce renal fibrosis; however, the pathways targeted ...
Oct 25, 2013
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Recreational drug use has been with us forever, and so have the challenges that this use brings to medicine and society. But the nature of the modern drug scene has changed to such an extent that the health systems of the ...
Sep 3, 2013
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China's police ministry accused executives of pharmaceutical supplier GlaxoSmithKline on Thursday of conducting a large and long-running bribery campaign to persuade doctors to prescribe drugs.
Jul 11, 2013
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U.S. and international regulators have seized more than $41 million in illegal medicines worldwide and shut down 1,677 websites as part of their ongoing fight against counterfeit drugs sold over the Internet.
Jun 27, 2013
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