Diseases, Conditions, Syndromes

Cystic fibrosis faithfully modeled in a human Lung Airway Chip

The inherited progressive disorder cystic fibrosis (CF) causes severe damage to the lungs, and other tissues in the body by affecting the cells that produce mucus, sweat, and digestive juices. In individuals carrying mutations ...

Medical research

Preventing calcification of bioprosthetic heart valves

A defective heart valve is the second most common form of heart disease. Most cases involve a narrowed aortic valve, but often the mitral valve can also be affected. Prostheses significantly increase the life expectancy of ...

Medical research

Stem cells and mathematical models: The future of medical research

Human induced pluripotent stem cells (hiPSCs), which can be differentiated into cardiac myocytes, are used in a wide variety of applications such as developing patient-specific disease models, or the evaluation of novel therapeutic ...

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