Medical research

Protein twist and squeeze confers cancer drug resistance

In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS), discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of ...

Health

Contact lenses for diagnostic and therapeutic use

Human bodily fluids and secretions contain molecules known as biomarkers that contain a wealth of information about the body's health and the presence of disease. Among secretions such as tears, sweat and saliva, tears are ...

Medical research

An unconventional ion channel

Scientists at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified the first mechanosensitive ion channel to be found in an intracellular vesicle system. It responds to concentration changes within the vesicle, ...

Cardiology

How is the heartbeat regulated?

The heart can stably maintain blood flow—at rest or under stress—over a lifetime. Using a mouse model, an LMU team has now uncovered the role played by a specific class of ion channels in controlling the heart rate.

Neuroscience

New mechanism affecting nerve impulses discovered

Researchers at Linköping University, Sweden, have discovered a new mechanism by which substances can open a certain type of ion channel and thereby regulate nerve impulses. The study, published in the scientific journal ...

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