Medical research

Fat tissue's "iron sink"

Adipose tissue, commonly called "body fat," stores excess fatty acids and supplies it back when the need arises. Finely balanced iron levels are important for the health of adipocytes, the cells that make up adipose tissue. ...

Diseases, Conditions, Syndromes

Treatment benefits patients with thalassaemia and HCV

Many individuals with the blood disorder thalassaemia also carry the hepatitis C virus (HCV) due to contaminated transfusions before 1990. Due to the co-existence of iron overload (from repeated blood transfusions), these ...

Medical research

New insights into the regulation of cellular iron

Northwestern Medicine scientists have identified a novel pathway that regulates cellular iron, which could lead to new therapies for patients with either an overload or deficiency of iron.

Diseases, Conditions, Syndromes

Discovery may help patients beat deadly pneumonia

Researchers have found that a hormone responsible for controlling iron metabolism helps fight off a severe form of bacterial pneumonia, and that discovery may offer a simple way to help vulnerable patients.

Medical research

Study proposes new protocol for treatment of thalassemia

Iron accumulation in myocardial cells, potentially resulting in heart failure or fatal arrhythmia, is one of the complications most feared by patients with thalassemia major, a hereditary disease also known as Mediterranean ...

Medical research

Drug-like peptides show promise in treating two blood diseases

New research suggests that synthetic peptides called minihepcidins may potentially treat two serious genetic blood diseases in children and adults. Although those diseases, beta-thalassemia and polycythemia vera, have opposite ...

Medical research

MRI effectively measures hemochromatosis iron burden

(HealthDay)—Magnetic resonance imaging (MRI) is an accurate and safe tool for the detection of low levels of iron overload in patients with hereditary hemochromatosis, according to a letter to the editor published online ...

Medical research

New study links excessive iron in cells with AMD, other diseases

In a new University of Kentucky study published today in Cell Reports, a leading scientific journal in cell biology, researchers describe a new molecular mechanism that contributes to age-related macular degeneration (AMD) ...

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