Genetics

Gene correction as a possible therapy for iron storage disease

Hereditary primary haemochromatosis is one of the most common inborn errors of metabolism in Europe. In this disorder, also known as iron storage disease, the body is overloaded with iron. The excess iron accumulates in organs ...

Diseases, Conditions, Syndromes

Anemia is undertreated in adults with low kidney function

In an analysis of outpatient data from over 5 million adults, hemoglobin level measured < 10 g/dl in more than 20% with advanced kidney disease, but less than 4% were treated with erythpoiesis-stimulating agents, and iron ...

Gerontology & Geriatrics

Older people with anemia and weak muscles face higher risk of dying

A study by researchers at the Federal University of São Carlos (UFSCar) in Brazil and University College London (UCL) in the United Kingdom shows that a combination of anemia and weak muscles in older people heightens the ...

Diseases, Conditions, Syndromes

Iron buildup in brain linked to higher risk for movement disorders

A disorder called hereditary hemochromatosis, caused by a gene mutation, results in the body absorbing too much iron, leading to tissue damage and conditions like liver disease, heart problems and diabetes. Scant and conflicting ...

Oncology & Cancer

Leukemia vulnerability discovered causing drug sensitivity

All human tumors originating from various tissues share a series of properties that define them, including the ability to prevent cell death. Instead, healthy organs induce programmed cell death or apoptosis to balance their ...

Health

Moderate drinking linked to brain changes and cognitive decline

Consumption of seven or more units of alcohol per week is associated with higher iron levels in the brain, according to a study of almost 21,000 people publishing July 14 in the open access journal PLOS Medicine. Iron accumulation ...

page 9 from 40