The severity of immune-mediated intestinal diseases such as graft-versus-host disease (GVHD) or inflammatory bowel diseases is known to be associated with alterations in the gut microbiome, but what leads to such disruption ...
Feb 2, 2023
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21
Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE)—the most common form of the chronic autoimmune disease lupus.
Jan 13, 2023
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156
A multi-institution study led by Rohan Dharmakumar, Ph.D., of Indiana University School of Medicine, has identified that iron drives the formation of fatty tissue in the heart and leads to chronic heart failure in about 50% ...
Nov 1, 2022
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1286
Two proteins ensure that cells can take up iron when needed. If both control proteins are switched off in mice, the animals develop severe anemia, as expected. At the same time, surprisingly, a cell type of the innate immune ...
Oct 7, 2022
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67
With its irregularities and anatomical complexities, the root canal system is one of the most clinically challenging spaces in the oral cavity. As a result, biofilm not fully cleared from the nooks and crannies of the canals ...
Aug 9, 2022
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53
A disorder called hereditary hemochromatosis, caused by a gene mutation, results in the body absorbing too much iron, leading to tissue damage and conditions like liver disease, heart problems and diabetes. Scant and conflicting ...
Aug 1, 2022
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1011
Consumption of seven or more units of alcohol per week is associated with higher iron levels in the brain, according to a study of almost 21,000 people publishing July 14 in the open access journal PLOS Medicine. Iron accumulation ...
Jul 14, 2022
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333
If a woman experiences chronic stress late in her pregnancy, it can affect her fetus' ability to absorb iron by as much as 15%, according to a study led by UW Medicine researchers in Seattle.
Jul 7, 2022
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68
Micronutrient deficiencies can promote inflammation and render the immune system particularly sensitive to allergenic substances. In particular, iron deficiency signals danger to immune cells and leads to a more pronounced, ...
Jun 7, 2022
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122
Next-generation drugs against the sometimes fatal disease amebiasis could result from a RIKEN researcher's new strategy targeting a source of iron that an infectious protozoan parasite needs to proliferate.
May 9, 2022
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