Building a map of the complex human brain and its approximately 100 billion individual neurons is no easy task. As a precursor to tackling that monumental challenge, researchers have started off with something smaller and ...
Oct 11, 2021
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Researchers from HSE University have discovered nucleotide sequences characteristic of microRNA isoforms (microRNAs with errors). The discovery will help predict errors in microRNA behavior and create drugs that can detect ...
Jul 21, 2021
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KRAS was one of the first oncogenes to be identified, a few decades ago. It is among the most common drivers of cancer and its mutations can be detected in around 25 percent of human tumors. The development of KRAS inhibitors ...
Jul 19, 2021
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A new study identified an adenovirus gene therapy vector carrying a VEGF isoform. It can improve uterine blood flow in placental insufficiency, as reported in the peer-reviewed journal Human Gene Therapy.
Dec 16, 2020
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Researchers at the Francis Crick Institute have identified a variant of the SARS-CoV-2 cell receptor ACE2, which is driven by antiviral interferon signals. The virus is not able to bind to this variant, dispelling concerns ...
Oct 23, 2020
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A study led by the IBB-UAB has identified the molecular mechanism through which a protein carrying genetic mutations associated with limb-girdle muscular dystrophy type 1G accelerates its tendency to form amyloid fibrils ...
Jan 29, 2020
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Rats are commonly used in nonclinical pharmaceutical studies to investigate the safety, efficacy and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via ...
Feb 21, 2019
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The discovery of pluripotent stem cells, which have the ability to differentiate into the huge range of different cell lineages that make up the human body, signaled the start of a new era in biological science and medicine. ...
Dec 19, 2018
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The brain can discriminate over 1 trillion odors. Once entering the nose, odor-related molecules activate olfactory neurons. Neuron signals first accumulate at the olfactory bulb before being passed on to activate the appropriate ...
Oct 19, 2018
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How is it possible that so many different and highly specific neuron types arise in the brain? A mathematical model developed by researchers from the University of Basel's Biozentrum demonstrates that different variants of ...
Sep 26, 2018
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