Genetics

Genes identify transplant rejection

Acute rejection after kidney transplantation occurs in about 15%–20% of patients despite immunosuppressive therapy. Rejection is usually heralded by an increase in the patient's serum creatinine (a marker of kidney function), ...

Diseases, Conditions, Syndromes

Identifying key regulators of kidney injury

(Medical Xpress)—Micro-RNAs (miRNAs) are a recently discovered class of RNA molecules that regulate how genes are expressed. UCD researchers led by Conway Fellow, Professor Catherine Godson are studying the role of miRNAs ...

Diseases, Conditions, Syndromes

Global effort to standardize diagnosis of kidney disease

Kidney disease is a major health concern worldwide. It's estimated that 1 in 3 American adults are at risk of developing kidney disease, and 26 million adults already have kidney disease. Many are undiagnosed. Because kidney ...

Surgery

Protein-based urine test predicts kidney transplant outcomes

Levels of a protein in the urine of kidney transplant recipients can distinguish those at low risk of developing kidney injury from those at high risk, a study suggests. The results also suggest that low levels of this protein, ...

Diseases, Conditions, Syndromes

TGen method isolates biospecimens for treatment of kidney disease

Researchers at the Translational Genomics Research Institute (TGen) have developed a method of isolating biospecimens that could lead to a less costly, less invasive and more accurate way of diagnosing chronic kidney disease, ...

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